NOVELREN

S2017/BMD-3751 (NOVELREN-CM)

Enfermedad Renal Crónica: Nuevas Estrategias para la Prevención, Diagnóstico y Tratamiento

PUBLICACIONES

  • de Frutos S, Luengo A, GarcíaJérez A, HatemVaquero M, Griera  M, O’Valle F, RodríguezPuyol M, RodríguezPuyol D, Calleros L. Chronic kidney disease induced by an adenine rich diet upregulates integrinlinked kinase (ILK) and its depletion prevents the disease progression .Biochim Biophys Acta Mol Basis Dis. 2019: 1865(6). 1284-1297. 
  • Rodriguez P, Sassi Y, Troncone L, Benard L, Ishikawa K, Gordon RE, Lamas S, Laborda J, Hajjar RJ, Lebeche D. Deletion of deltalike 1 homologue accelerates fibroblastmyofibroblast differentiation and induces myocardial fibrosis. European Heart Journal. 2019:40(12). 967-978. 
  •  CanoMegías M, GuisadoVasco P, Bouarich H, de Arribade la Fuente G, de SequeraOrtiz P, ÁlvarezSanz C, RodríguezPuyol D. Coronary artery calcification in patients with diabetes mellitus and advanced chronic kidney disease. Endocrinología, Diabetes y Nutrición. 2019:66.297-304. 
  • Lavoz C, Poveda J, MarquezExposito L, RayegoMateos S, RodriguesDiez RR, Ortiz A, Egido J, Mezzano S, RuizOrtega M. Gremlin activates the Notch pathway linked to renal inflammation.Clin Sci (Lond). 2019:132(11). 1097-1115.
  • Godzien J, Kalaska B, AdamskaPatruno E, Siroka J, Ciborowski M, Kretowski A, Barbas C. Oxidized glycerophosphatidylcholines in diabetes through non-targeted metabolomics: Their annotation and biological meaning. J Chromatogr B Anal Technol Biomed Life Sci. 2019:1120.62-70. 
  • Lavoz C, Matus YS, Orejudo M, Carpio JD, Droguett A, Egido J, Mezzano S, Ruiz Ortega M.  Interleuki-17A blockade reduces albuminuria and kidney injury in an accelerated model of diabetic nephropathy. Kidney International  2019: 95(6). 1418-1432. 
  • Moreno JA, GomezGuerrero C, Mas S, Sanz AB, Lorenzo O, RuizOrtega M, Opazo L, Mezzano S, Egido J. Targeting inflammation in diabetic nephropathy: a tale of hope. Expert Opin Investig Drugs. 2018: 27(11). 917-930.
  • RayegoMateos S, MorgadoPascual JL, RodriguesDiez RR, RodriguesDiez R, Falke LL, Mezzano S, Ortiz A, Egido J, Goldschmeding R, RuizOrtega M. Connective tissue growth factor induces renal fibrosis via epidermal growth factor receptor activation. J Pathol. 2018:244(2).227-241
  • Gutiérrez S, Morón M, Griera M, Sucunza D, Calleros L, GarcíaJérez A, Coderch C, Hermoso FJ, Burgos C, RodríguezPuyol M, de PascualTeresa B, DiezMarques ML, Jimenez A, ToroLondoño M, Rodríguez Puyol, Vaquero JJ . Discovery of potent calpain inhibitors based on the azoloimidazolidenone scaffold. Eur J Med Chem. 2018:157. 946-959.